Review of Using Amniotic Membrane Derivatives for the Treatment of Chronic Wounds

Schmiedova,I.; Dembickaja, A.; Kiselakova, L.; Nowakova, B.; Slama, P. Using of Amniotic Membrane Derivatives for the Treatment of Chronic Wounds. Membranes2021,11,941. https:// doi.org/10.3390/membranes11120941

MDPI_2021_membranes-11-00941

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This paper provides a comprehensive review of the therapeutic applications of amniotic membrane (AM) derivatives in chronic wound treatment. Highlighting AM’s regenerative qualities, the study explores its effectiveness in promoting wound healing through mechanisms like pain relief, anti-inflammatory properties, angiogenesis, and reduced scarring. AM's high levels of growth factors make it an ideal material for enhancing cell proliferation and wound repair, with an impressive 86-90% success rate in treated cases.

The study also delves into various preservation methods for AM, such as cryopreservation and lyophilization, and compares treatment outcomes. The review underscores AM's versatility, noting applications across medical fields like ophthalmology, orthopedics, and gynecology, positioning AM derivatives as a promising, natural solution in chronic wound management. This review underscores AM’s potential to advance wound care, reduce hospitalizations, and improve patient outcomes. At WoundFree, we’re committed to raising awareness about the importance of early detection and proper wound care. For those at risk, regular screening and preventive measures can make a profound difference.